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Blond hair in Melanesia genetically distinct from that of Europeans

04 May
Anthropology.net calls my attention today to this paper:

Abstract
Naturally blond hair is rare in humans and found almost exclusively in Europe and Oceania. Here, we identify an arginine-to-cysteine change at a highly conserved residue in tyrosinase-related protein 1 (TYRP1) as a major determinant of blond hair in Solomon Islanders. This missense mutation is predicted to affect catalytic activity of TYRP1 and causes blond hair through a recessive mode of inheritance. The mutation is at a frequency of 26% in the Solomon Islands, is absent outside of Oceania, represents a strong common genetic effect on a complex human phenotype, and highlights the importance of examining genetic associations worldwide. 

Actually natural blond hair is also found in West and Central Asia and North Africa, and red hair even in the Horn of Africa now and then. But I guess that’s what the authors mean by “Europe”, duh! It’s also found occasionally among South Asians, specially the young, and among SE Asians regardless of age.
Whatever the case with the authors ethno-geographic misconceptions, the results are still most interesting: the gene causing blond hair among Melanesians (and some relatives like Fijians) is not the same as those involved in blond hair in Europe. Mind you that it is not clear yet which are these European genes of blondism but it is clear that the Melanesian allele is not it either. 
There is also an article at New Scientist.
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Posted by on May 4, 2012 in human genetics, Melanesia, pigmentation

 

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